All natural. The supreme green bone - dogs love! Freshens breath. Promotes healthy teeth & gums. Easy to digest. For dogs of all shapes & sizes under 35 lbs! Stay fresh pouch! Easy to digest (Based on an independent laboratory side-by-side study, comparing which dental bone was first consumed by dogs). Tested for safety (Based on independent laboratory tests performed by Summit Ridge Farms). Sterilized by irradiation for freshness & health. Made in China.